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The increased frequency of CFU-GM cells with their intensive proliferation allowed faster restoration of the damaged CFU-GM compartment than was seen in the case of repeated daily administration of the cytostatic drug (25 or 50 mg kg−1) together with rosiglitazone for 7 consecutive days.
Sperm development again starts with intensive proliferation of a pool of interstitial cells in the upper body column resulting in large clusters of sperm cell progenitors (Littlefield et al., 1985; Munck and David, 1985).
The normal liver architecture was lost and replaced by regenerating nodules that were separated by fibrous septae extending from the central vein to the portal triad and accompanied by intensive proliferation of the bile duct together with invasive inflammatory cells.
The increased c-MYC expression level in the cholesteatoma matrix compared to that of the atheroma matrix might explain the more aggressive behavior of cholesteatoma that results in clinical complications and it also explains its more intensive proliferation.
As shown in Table 2, the HbF blood vessels were distributed within the tumour and in the lamina propria, where the most intensive proliferation of fine blood vessels was noted.
In tumours with weak proliferation (low Ki-67), the TAA index was closely associated with better prognosis, while all of the patients with intensive proliferation had poor prognosis (Supplementary Figure 4).
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PHB/20% HA induced more intensive MMSC proliferation compared to pure PHB, which are 31% ± 6.1% and 20% ± 5.7%% respectively when p = 0.039.
The bone marrow is a site of intensive cell proliferation and cell death.
Moreover, Table 1(c) and Figure 3B suggest that significantly shortening DC life span, e.g., by differentially eliminating them, may give rise to intensive SC proliferation.
In human cerebellum, intensive cell proliferation occurs within the external granular layer between the 28th and 34th gestational weeks and is still active by the fifth postnatal month (Abraham et al., 2001).
Recombinant G6PI induced intensive T-cell proliferation.
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