This ongoing accompaniment that is, continual coaching and feedback to providers during the "learning curve" of implementation represents a labor-intensive necessity for behavioral research but is an aspect of ongoing supervision that is often overlooked during programmatic implementation.
Specifically, the increased knowledge of AML biology has not yet obviated the necessity for intensive cytotoxic chemotherapy.
One of the study's difficulties was the necessity for intensive sampling to recover the plasma.
A strategic biological role of rhoptry proteins (ROP) in parasitophorous vacuole biogenesis and virulence of the parasite creates a necessity for an intensive study on the serological activity and immunogenicity of newly developed recombinant ROP antigens.
Of the minority (35.3%) of miRNAs that were most significantly upregulated in the tumor tissues, the outlier miR-122 was initially identified as a tumor-suppressor in other cancers [52], [53], indicating the necessity for the intensive investigation of well-known cancer-associated miRNAs in different kinds of tumors for full elucidation of their functional roles in tumorigenesis.
The presence of a large number of immune system genes may reflect the epithelial character of the tissue and also the necessity for tight control on intensive processes such as, regeneration of the neuron population which involves cytokines and immune cells.
If education is going to take advantage of the Internet, the necessity for constructing new, knowledge-intensive systems for collaborative work will also be shown.
Both univariate and multivariate analysis revealed that EDC status had no effect on graft or patient survival, the necessity for retransplantation, the length of intensive care/intermediate care unit stay, mechanical ventilation, complications, or posttransplant laboratory findings.
Therefore, basic knowledge of the mechanisms of action of each of these devices, as well as their advantages and disadvantages, becomes a necessity for the respiratory care and intensive care practitioner.
5 The recent emergence of N. gonorrhoeae isolates with decreased susceptibility and resistance to the currently recommended treatment guidelines of the Centres for Disease Control and Prevention, including extended-spectrum cephalosporins (ESC), has further established the necessity for a standardised, reliable, economical, less labour intensive and reproducible susceptibility testing method.
The necessity for antigen sparing and the problem of cross-reactivity has sparked an intensive search for new immunological adjuvants [10], [56].
