Comparative studies of the effects of recombination rate on genome architecture and sequence evolution across distantly related species require both whole genome sequences and data-intensive estimates of recombination rates [ 2– 4].
This will be achieved by combining information from the trial (the impact on HbA1c and the incremental cost of the structured intensive intervention) with estimates of other parameters from the literature.
Imperfect detection from less intensive sampling method results incorrect estimates of abundance of herpetofauna.
A more recent intensive validation exercise has produced estimates of Sp of 97.3% for the I-ELISA, 98.2% for CHEKIT and 97.2% for the Ceditest (the C-ELISA).
For example, prior to the establishment of intensive surveillance activities for smallpox, estimates of reporting rates in Indonesia and West Africa varied from <1% of cases to 8% in urban areas [Keja (1968) reported in 3, 17].
For C. elegans, the reference genome sequence is complete and our manual annotation was intensive enough to permit good estimates of the number of defective genes for each family, as summarized in Additional file 9.
Two trials, 18 19 jointly accounting for 44% of the weight of these results, reported point estimates of effects that suggested a greater likelihood of smoking cessation in the less intensive intervention group compared with the more intensive intervention group.
However, in many cases, obtaining direct estimates of the level of prenatal hormone exposure may be difficult or labour-intensive.
Detection probability is estimated from the units surveyed with both rapid and intensive methods and the estimate of detection probability is used to convert the counts from the rapid method to a population estimate.
Thus, for studies where population size is of primary importance, the DS method will provide reliable estimates only if the intensive method provides an unbiased estimate of all birds present in units surveyed.
Where population estimation is a primary objective, the DS method may be preferable to the DO method if the assumptions of the method can be met, notably that the intensive method provide an unbiased estimate of the number of individuals present.
