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Apples undergo two distinct phases during growth: a phase of intensive cell division which lasts typically 3-5 weeks after full bloom, followed by a phase of cell expansion when cell division ceases [ 2].
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Together, these studies reveal an in vitro in vivo relationship of the 2,5,6-trisubstituted benzimidazoles that serves as a criterion for advancing this class of cell division inhibitors into more resource intensive in vivo efficacy models such as the long-term murine model of tuberculosis and Pre-IND PK/PD studies.
The intensive light microscopic studies of the earlier cytological era on cell division and chromosomes, which laid the basis for this understanding are very comprehensively covered by WASSERMANN (1929) in his masterly contribution "Wachstum und Vermehrung der lebendigen Masse" in this handbook.
DOI: http://dx.doi.org/10.7554/eLife.04960.009 Although intensive investigations have revealed the mechanisms of cell polarity and asymmetrical cell division along the polarity axis, much less is known about how cells ensure the correct temporary order of cell polarization and cell division.
Cell length, cell growth and cell division.
The egg then undergoes a cell division.
Reproduction is by vegetative cell division only.
This initiates the process of cell division.
The germinal epithelium undergoes cell division, however.
It goes into the cells, creates lesions, halts cell division, and the cells eventually die.
Kinetics of cell division in epidermal maintenance.
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