One potential limitation of this investigation is the possibility that despite intensive case-finding efforts employing multiple methods, other IP cases were not identified.
This was the result of a policy of intensive case-finding and the return of infected travellers during that period.
Furthermore, as reported by Cowling et al. (11 ), intensive case-finding activities might have produced more comprehensive diagnosis and reporting, thereby capturing less severe cases.
Overall, 24% of cases were diagnosed as a result of active case finding on the medical and intensive-care wards.
Examples of such measures include targeted delivery of individualized, albeit expensive treatments, resource-intensive active case finding, and, in extreme cases, isolation [ 75, 76].
Because early case finding was most intensive among high school children associated with school outbreaks, our cohort may have been biased in favor of households where the index case-patients were children; however, this would not explain a lower secondary attack rate among adult household contacts.
Based on the evidence included in this review, the findings suggest that intensive case management, providing insurance information, application assistance and communicating with the insurer to assist with enrolment probably help increase insurance coverage of children in the US.
Singapore's outbreak containment strategy focused primarily on intensive vector control and rapid removal of infectious human reservoirs through active case finding and isolation.
Programmes which require active case finding and subsequent follow-up, such as tuberculosis or leprosy control are time and resource intensive operations.
