Sentence examples for intensive administration from inspiring English sources

Paradoxically, because of more prolonged time and less intensive administration, the number of CMF cycles fared better among patients who received concomitant radiotherapy.

A common theme was that because the scheme was logistically difficult to deliver, even with resource intensive administration it was still only achieving low uptake.

The drugs also pose several other problems; they can be expensive, require intensive administration programmes which are unrealistic in a resource poor setting and some are toxic to patients.

Non-anion gap hyperchloremic metabolic acidosis frequently develops during DKA treatment and is believed to occur due to urinary losses of ketoanions, which are needed for bicarbonate regeneration, and preferential reabsorption of chloride in proximal renal tubule secondary to intensive administration of chloride-containing fluids.

This, together with the high dose of LV, and a labour-intensive administration schedule, place high demands on healthcare resources (Ross et al, 1998).

Plantar-palmar erythrodysesthesia, an epithelial toxicity observed in patients receiving protracted infusions or repeated dose-intensive administration of doxorubicin (Samuels et al, 1987; Bronchud et al, 1989), and the dose-limiting side-effect of caelyxs™ (Ranson et al, 1997), was not observed with DaunoXome in this study.

Toxicities and intensive intravenous administration, unfortunately, are major concerns.

The patients were randomly assigned to an active treatment or a placebo group and received intensive oral administration of Artemisia pollen extract over a 50-day course.

By comparison, the association with the presence of B symptoms was weak (adjusted Odds Ratio = 1.34, 95% CI 1.03 1.75); and no associations between intensive chemotherapy administration by sex or area-based deprivation were detected.

Weng et al. (20) recently reported that 1 week of intensive insulin administration in patients with newly diagnosed type 2 diabetes resulted in remission of diabetes in half of the patients after 1 year of follow-up.

The general belief is that intensive insulin administration is associated with increased hypoglycemic risk, but studies have shown that in fact there is a significant decrease in the risk of hypoglycemia with continuous subcutaneous insulin injection when compared with multiple daily injection.