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Maybe, she said, it is because it is not simple to get back to life after months of the daily intensity of the trial.
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However, the intensity of these trials limits their scalability to real world settings.
The mean duration and intensity of the cycling trials was 1 h and 57.5 % VO2max (range, 55 60 % VO2max), respectively.
The mean duration and intensity of the walking trials was 37.5 min (range, 30 45 min) and 55%% VO2max (range, 50 60 % VO2max), respectively.
Such an approach alleviates the intensity of a trial and error process to NN design and additionally ensures good generalisation.
Normalized, background-subtracted ΔF/F traces were calculated from these according to the equation, (3) (Δ F F ) i = F i F b a s e l i n e − 1 where F i is cell fluorescence on frame- i and F baseline is the median fluorescence intensity of the cell on that trial.
As the intensity of the whisker stimulus diminishes and trial-to-trial failure rates increase for a given cell, the cell would appear to drop out of the population.
Results showed that similar to the Xenopus/zebrafish comparison, tadpoles initially possess no preference for either low intensity red or high intensity blue light at the beginning of the trial (Fig. 7, pre-training).
The intensity of the follow up in this trial (fortnightly home visits by the physiotherapist) is greater than the Otago program (consisting of four primarily instructive home visits) due to the need for maintaining sufficient challenge in a clinical group that are likely to increase their ability over time and the complexity of pre-existing medical conditions.
As blinding of participants in dietary trials is difficult to achieve, we scored the trials based on the intensity of the dietary advice given to the randomised groups.
However, it was not possible to systematically quantify the intensity of interventions across trials and uncertainty on optimal intensity, limits the ability to generate reliable recommendations for clinical practice.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com