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The histologically measured damaged area fraction was positively correlated with the micro-CT measured damaged area fraction and with the median CT intensity of the bone, indicating that the micro-CT images can detect microdamage in trabecular bone with sufficient accuracy to differentiate damage levels between samples.
Magnetic resonance imaging showed diffuse low signal intensity of the bone marrow on T1-weighted images, suggesting myeloproliferative disease.
Modic changes are recognized on magnetic resonance imaging (MRI) scans as alterations in signal intensity of the bone marrow adjacent to a degenerated disc.
When the ratio of fat and non-fat cells in the bone marrow is not altered or only slightly altered, the T1 and T2 signal intensity of the bone marrow remains normal.
These observations have contributed to the current standard of care practice of reducing the intensity of the bone marrow transplant conditioning regimens with significantly improved short-term outcomes [ 8].
Regional decreased signal intensity of the bone marrow in T1-weighted images and increased signal intensity on T2-weighted images represented an accumulation of 'bone marrow water', which could be confirmed by biopsy.
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Variations in the cellularity of bone marrow are reflected in the signal intensity of the bones on high b-value images (Fig. 2).
The median intensity of the treated bone tissue was compared between groups.
Proton density images of the diseased horse had a clear increase in signal intensity of the compact bone at the proximo-axial margin of the PSBs compared to the images of the non-diseased horse.
On WB-DWI, lytic/infiltrative skeletal metastases appear as focal or diffuse areas of high-signal intensity on high b-values on a background of lower signal intensity of the normal bone marrow [ 4, 5].
In adults, the signal intensity of the normal bone marrow is typically hyperintense to surrounding muscle and intervertebral disks on T1-weighted MR images and hypointense to surrounding muscle on STIR- or fat saturated T2-weighted MR images.
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