These include recession of cell-mediated immunity, obstructive uropathy and neurogenic dysfunction related bladder defense alteration, bacterial receptivity intensification of uroepithelial cells [ 23], fecal and urinary incontinence related contamination, urethral instrumentation and catheterization, and hormone related antibacterial factors reduction in the prostate and vagina [ 24].
The majority of patients will require continual intensification of treatment as beta cell function deteriorates and endogenous insulin production declines [ 2].
Because of the inhibition of nuclear translocation of EGFR, nimotuzumab and also cetuximab, both antibodies, induce radiosensitization increasing the percentage of dead/dying cells and the yield of γ-H2AX foci being able to promote intensification of radiosensitivity of malignant cells expressing EGFR and offer potential improving of therapeutic index of radiotherapy [ 93].
Currently, MRD assessment is increasingly applied in clinical practice for monitoring ALL that may provide physicians enough information to intervene the planned treatment of a patient earlier with intensification of chemotherapy or allogeneic stem cell transplantation.
Co-cultured cells revealed intensification of the 72 kDa bands as well as the appearance of lower molecular weight bands (Fig. 4B).
Even though the mechanisms through which benzophenones impair cell growth and induce apoptosis are still under investigation, some studies suggest an anti-microtubule action during cell division or the intensification of caspase-3 activity [ 25, 28, 29].
During this period, E. cloacae DNA appeared stable immediately after inoculation The observed intensification of the biogas by E. cloacae was proportional to its cell number.
Nitrogen fixation is highly sensitive to the presence of oxygen, so Azotobacter developed a special defensive mechanism against oxygen, namely a significant intensification of metabolism that reduces the concentration of oxygen in the cells.
Interestingly, these metabolites generally exhibited type "AC" profile during flux-sum intensification, indicating that the intensification of any essential metabolite in parallel pathways is very detrimental to the cell growth.
Due to the inevitable decline in β-cell function characterizing T2D, patients typically require progressive intensification of therapy when diet, exercise, and metformin cannot maintain adequate glycemic control.
