Using FLIM-FRET and co-immunoprecipitation we additionally show extended and more intense interaction of the variant p.C284A with ASC compared with WT caspase-1.
If you use a compound that kills, the selective pressure for a resistant variant is intense.
Indeed, it's quite possible that no culinary tradition (except for the Hot Pocket) is more thoroughly American than barbecue, with its different variants creating intense arguments and even more intense blood pressure issues across this great land.
H14A/H67A(B) elicited pH-dependent sweetness, but the other two variants elicited intense sweetness even at pH 8.0 (Fig. 3, double).
Intense exploration of regulatory variants has been accelerated by new genomic technologies.
Nevertheless, the unique spot observed for motile 57B cells (rough variant) were more intense than that observed for planktonic 57B cells.
Brel's original, inspired by his mistress Zizou, is more cloyingly intense when compared to other variants, almost embarrassingly so at times.
Variants with the most intense and red-shifted fluorescence emission were used as templates in the subsequent round of library construction.
As demonstrated in Figure 8, the evolution process had succeeded in creating variants that demonstrated more intense staining in an immunofluorescence application.
First, a cell culture may be heterogeneous for a copy number variant, leading to a less intense signal than if the variant was fixed.
At the same time, the intense growth of lateral roost in these variants was observed (Fig. 1c, d).
