In the last few years, intense efforts have been devoted to the development of new photoactive materials for solar-driven water purification.
Mobile Laser Scanning is well-established for achieving geo-reference point clouds and imagery depicting the reality in an accurate and productive manner and intense efforts have been made to implement automatic methods for extracting geometric and semantic useful information.
With this, intense efforts have been made to inhibit the activity of the EGFR and HER2 by designing antibodies against the ligand binding domains (cetuximab, panitumumab and trastuzumab) or small molecules against the tyrosine kinase domains (erlotinib, gefitinib, and lapatinib).
Since the discovery of the intercalative binding mode, almost half a century ago, intense efforts have been devoted to design, synthesize and test new small molecules that can bind nucleic acids with improved recognition and affinity.
Intense efforts have been made to introduce Basque as a vehicle of private primary education, and a written standard, Euskara Batua ("Unified Basque"), has found widespread albeit not universal acceptance.
In recent years, intense efforts have been devoted to the studies of effects of tunneling coupling between electron states in semiconductor heterostructures with quantum dots (QDs), which offer much promise in the development of high-speed lasers [1], optical modulators [2], and amplifiers [3].
Intense efforts have been made to get information about the molecular basis of GR activity.
In the past decade, intense efforts have been made to address the mechanism by which BRCA1 is regulated, especially its phosphorylation by the checkpoint kinase and transcriptional regulation.
To improve glucocorticoid pharmacological profile, intense efforts have been made to obtain more information about the molecular mechanisms that underlie beneficial and unwanted glucocorticoid properties, and to design new selective compounds.
Intense efforts have been made to understand the effect of teriparatide on antiresorptive therapy and vice versa.
Since the identification of BACE1, intense efforts have been underway to develop small-molecule BACE1 inhibitors as drugs for AD.
