CTM supports a faster and more intense dissemination of dengue virus serotype 2 (DENV2) than Rex-D (Bennett et al. 2002; Salazar et al. 2007).
High dispersal distances and densities of Ae. aegypti in Rio have been suggested as important contributors to the intense risk of dengue epidemic in the city (Maciel-de-Freitas et al. 2007, 2014).
An early and efficient virus clearance by direct or indirect NK functions is likely controlling virus replication, restricting intense immunological activation and the dengue immunopathology and therefore favouring a mild dengue disease.
Dengue causes an intense inflammatory process that involves the release of inflammatory cytokines, activation of the complement system and platelets, and endothelial injury, which results in increased vascular permeability with a consequent loss of intravascular fluid [ 37, 38].
Patients progressing to shock (dengue shock syndrome DSS) show intense abdominal pain or tenderness, persistent vomiting, weak pulse, and hypotension.
People who have antibodies to dengue might mount a less intense immune response to Zika, which might make it more likely that the virus crosses the placenta and infects a fetus.
4, 5 On both islands, the 2010 epidemic was particularly intense, with 10% of the population having suspected dengue.
Infection by dengue virus can cause high fever and intense joint and muscle pain.
18 Dengue transmission in northern Vietnam is less intense than the tropical southern regions, but dengue notifications have increased annually since 1999.
A landmark came in a 2005 Science paper, in which Xi Zhiyong, then at Johns Hopkins University in Baltimore, Maryland, and colleagues infected a mosquito species called Aedes aegypti, which is the main carrier for dengue fever, a debilitating viral disease that causes intense muscle and joint pains.
