The worst drought in recent years came in the summer of 1988, when a combination of intense heat and widespread moisture deficiency baked more than a third of the country for weeks.
Furthermore, the brains of NCL patients caused by Cathepsin D deficiency (CLN10 disease) show intense α-synuclein staining (23).
Silvicultural treatments have a lesser impact unless stands are suddenly released from intense competition by severe thinning or a nutritional deficiency is corrected by fertiliser application.
Current clinical recommendations suggest that children with a normal birth weight but rapid weight gain in the first few months of life leading to extreme obesity should be tested for congenital leptin deficiency when they show impaired satiety, intense hyperphagia, and food-seeking behavior (see Clinical phenotype of patients with congenital leptin deficiency) [6],[7].
Research in the regulation of the Fe deficiency response in plants has generated intense interest.
As human populations moved north with less intense UV exposure, selection pressures from vitamin D deficiency resulted in lighter skin pigment.
Nutrient deficiencies, especially of nitrogen, triggered more intense colour in maples as the trees attempted to lessen the effects of sunlight.Not everybody agrees that the main autumnal role of anthocyanins is protection from excess illumination.
Hence, energy deficiency results in injuries and poor recovery from intense training [10].
The nature and the level of T-cell immune deficiency in B-CLL are the object of intense investigations.
Roddick says that Gilbert's style is markedly different from that of his former coach, Tarik Benhabiles, a Frenchman who was all tennis, all the time: "Tarik's a really intense and emotional guy, and he's more about focusing on the deficiencies in your game, while Brad likes to focus more on how you can take advantage of the deficiencies in your opponent's game".
Babies are highly vulnerable to micronutrient deficiency up to age two, when they are in a period of intense physical, motor and cognitive growth.
