We have shown that in both stages of the parasite life cycle the more intense clusters are found in central positions and clusters of lower intensity localize towards the periphery.
From that era too came jewels: intense clusters of turquoise and coral at the neckline, especially effective when melding with a Japanese floral print or shown against the pure white of a slim evening dress.
In his 2009 book, "The Great Reset: How New Ways of Living and Working Drive Post-Crash Prosperity," Richard Florida argues that the modern economy requires a different layout: "The coming decades will likely see more intense clustering of jobs, innovation and productivity in a smaller number of bigger cities and city-regions," he writes.
In addition, an activation likelihood estimation (ALE) meta-analysis of the paired associates literature revealed that a higher degree of concordance was obtained when using the Lancaster transform in the form of fewer, smaller, and more intense clusters.
In both insect and human stages, the most intense clusters tend to be centrally located (Figures 4B and 4C).
DNA damage acquired in interphase would seem unlikely to exhibit such intense clustering of breaks within such well-circumscribed genomic regions.
The results indicate that intense clusters are a rare phenomenon that merit careful investigation, although aetiological insights are more likely to come from investigation of large numbers of cases.
One view of cancer clusters holds that the clustering in space and time of cases routinely occurs by chance (Bellec et al. 2006; McNally et al. 2002; Petridou et al. 1996), although investigations such as the EUROCLUS (Clustering of Childhood Leukaemia in Europe) study suggest that isolated intense clusters of childhood leukemia are rare (Alexander 1998).
On the basis of the recorded mass spectra, the most intense mixed cluster should be isolated and deposited on a support material, which is kept at a temperature low enough to avoid crystallization of the film during deposition.
The analysis results show that the larger the Z-score is, the more intense the clustering of high values (hot spot); and the smaller the Z-score is, the more intense the clustering of low values (cold spot).
