Astrogliosis is prominent, diffuse, and intense throughout affected CNS regions in transmissible spongiform encephalopathies such as Creutzfeldt Jakob disease (CJD) (Fig. 7b) and related prion diseases, especially if clinical symptoms have been of long duration.
PET-CT has been shown to have higher sensitivity than echocardiography in the detection of valve abscess, showing intense uptake in the affected valves (Fig. 15b) [7].
However, an inflammatory infiltrate in the skin was present in all animals, even in those without symptoms, and was more intense in the clinically affected dogs than in asymptomatic and control dogs (p = 0.006, Kruskal Wallis and Student-Newman-Keuls tests).
Even after thorough investigation, aetiological causes can be found in only 50% of cases. 2 Frequently, the cause is elusive or multifactorial, 36 leading to intense frustration for the affected woman and her healthcare team, as there is currently no effective treatment or therapy which can be offered.
The court rejected that argument: determining what constitutes a "substantial burden", it held, requires looking not at "whether the government mandate operates directly or indirectly, but on the coercion that the claimant feels to violate his beliefs", and in this case, the heavy fines mandated by the ACA ($100 per day per affected employee) constitute intense coercion.
Irrespective of kinetics, the affected parenchyma demonstrates intense enhancement compared to uninvolved tissue (Fig. 2).
Blood pool and delayed images typically show intense increased uptake in the affected joints (Fogelman et al. 2014).
PET scan revealed intense FDG uptake in the affected eyeball and left supraclavicular, mediastinal, right upper, and lower paratracheal and bilateral hilar lymph nodes.
Potential causes of this failure include waning of vaccine induced immunity, a relative mismatch between vaccine and outbreak strain, and intense social contact in the affected group (8 ).
Many diseases of the central nervous system are characterized and sometimes worsened by an intense inflammatory response in the affected tissue.
