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Hence, the recruitment process was thus shortened and consequently, smaller than intended sample size.
Two practices had issued NHSHC invitations to fewer than the maximum intended sample size at the time of study invitation, so no sampling was undertaken and all eligible patients from those practices were invited to participate.
If the actual sample size differed from the originally intended sample size for some other reason (for example, because of poor recruitment or revision of the target sample size), the explanation should be given.
Moreover, the longitudinal and prospective design is less vulnerable for measurement error, which is a risk of cross-sectional or retrospective studies.[ 54, 55] The intended sample size and the involvement of multiple hospitals (six general and one academic hospital) will improve the reliability of the results.
All of these subgroup analyses were underpowered, and even the full trial was much smaller than intended (the intended sample size was 1,620; achieved was 838).
Our intended sample size was 150 Chinese smokers aiming to identify mean differences in knowledge, beliefs, attitudes and practices related to smoking and experience in smoking cessation between age, gender, education and ethnicity groups.
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The intended sampling method is quota sampling.
To detect "medium" main or interaction effects (f ≥.25) with sufficient power = 0.8 in F-tests with α =.05 significance level, a cell sizes of n = 27 is needed, which we rounded to n = 30 to be "on the safe side", hence the total sample size intended was N = 180.
In subsequent studies, we intend to expand our sample size to investigate the incidence of TG13T5.
In light of this we intend to expand our sample size over a 5-year period and subject the data to multivariate regression.
We intend to increase the sample size by 25% to compensate for dropout and potential loss of power due to clustering of data, resulting in 160 participants (80 in experimental condition and 80 in control condition).
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