His intellectual defect was rather that of oversubtlety; he enjoyed the niceties of argumentation, was inclined to be captivated by the twists of his own ingenuity, and had a habit of using the reductio ad absurdum in dangerous places.
Though Asperger regarded it as a biological defect of affective contact — innate, inborn, analogous to a physical or intellectual defect — Kanner tended to view it as a psychogenic disorder, a reflection of bad parenting, and most especially of a chillingly remote, often professional "refrigerator mother".
The contract also demanded that workers pay the boss $58 if they left before the end of the yearlong contract, and $2,400 if they "stole intellectual property" by defecting to a rival eyelash maker.
In April of 2009, the Mights flew to Duke University, in Durham, North Carolina, to meet with a range of specialists, including a geneticist named Vandana Shashi, whose clinical practice focusses on children with birth defects, intellectual disabilities, and developmental delays.
Only large deletions are found in affected individuals that exhibit intellectual disability, muscular defects and several cranio-facial malformations.
Testing in medical practice began as a method to identify an etiology, often but not always de novo, in children with mental retardation (intellectual disability), birth defects, and other developmental disabilities.
Trisomy for human chromosome 21 (chr21) is the most frequent live-born aneuploidy and is the cause of Down syndrome (DS), whose main symptoms include intellectual disability, cardiovascular defects and craniofacial dysmorphisms [ 1].
"I can predict to you now that it is likely that the children who look reasonably normal, don't have any gross formation defects, might later on have issues that relate to subtle things like visual defects, or hearing defects, or intellectual landmarks children get as they develop.
DNA testing has become increasingly useful in the detection and treatment of various conditions, including cancer, intellectual developmental delays, birth defects, and diseases of unknown origin, and the cost of genetic analyses has dropped even as the speed with which their results are delivered has risen.
Consistent with these findings, we identified an individual with microcephaly, short stature, intellectual disability, and heart defects with a de novo c.505C>T variant leading to a p.His169Tyr change in PUF60.
High maternal blood PHE is associated with poor outcomes in offspring, including low birth weight, microcephaly, congenital heart defects, and intellectual disability.
