It is therefore imperative that the integrity of these measures be maintained when they are implemented in clinical trials and other research studies.
It correlates with vision-specific quality of life measures, providing information on clinical meaningfulness, and with the structural integrity of the retina measured by optical coherence tomography (OCT).
The roughness of the cell membrane is also an indicator of cell's health state [ 4, 5] and the skeletal integrity of the membrane, measured as surface roughness, is well correlated to the functional status of the cell, with a decrease of the membrane roughness seen in cells from diseased individuals [ 3, 6].
The quantity and integrity of the RNA was measured with NanoDrop (ThermoScientific) and used 3 µg RNA as template for SuperScript III RT (Invitrogen) and oligo dT 12 18 (Invitrogen) as specific primer for amplification of mRNA.
The quantity and integrity of the RNA was measured using a Nanodrop, and an Agilent 2100 BioAnalyzer RNA 6000 Nano Assay (Agilent Technologies, Amstelveen, the Netherlands).
Quantity and integrity of the RNA were measured with the RNA 6000 nano assay kit using an Agilent 2100 bioanalyser (Agilent Technologies, Germany).
The quality and integrity of the RNA were measured using NanoDrop spectrophotometry and Bioanalyzer (Agilent).
Generally the integrity of the cartilage is measured using signs of edema or fibrillation of the cartilage [ 16].
The integrity of the OCJ was measured as the number of channels crossing the OCJ into the cartilage of the whole section of medial tibial plateau.
Pelleted DNA was resuspended in 1X TE and the integrity of the samples was measured using a spectrophotometer (NanoDrop 1000, Themo Scientific, Waltham, MA).
