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The use of vegetation indices as indicators of the forest integrity has been shown to be a useful tool for environmental planning and also for conservation strategies.
Although compromised BBB integrity has been shown in some lysosomal storage diseases (reviewed in [16]), this is the first report demonstrating microvascular endothelial cell damage in brains of mice modeling MPS III B. The numerous vacuoles detected in endothelial cell cytoplasm, even in early symptomatic mice, may degrade cell function leading to BBB impairment.
Golgi ribbon integrity has been shown to be important for proper Golgi glycosylation as it allows for an even distribution of Golgi resident enzymes across the entire organelle.
White matter integrity has been shown to be important for cognitive performance, but very few studies have taken this into account when investigating the effects of IR in animal models.
Under temperature selection, adaptive changes in zymolyase and Micafungin resistance could be expected inasmuch as cell wall integrity has been shown to play a key role in thermal stress response [ 63].
While disease progression is frequently assessed by quantifying intraarticular cartilage loss, changes in subchondral bone also play a key role in the pathogenesis of knee OA. 8 In fact, subchondral bone trabecular integrity has been shown to be a strong predictor of disease progression.
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Other factors such as meniscal pathology and cruciate ligament integrity have been shown to affect the incidence of OA and subsequent cartilage loss [ 41, 42].
Changes in endothelial barrier integrity have been shown to be related to neutrophil β2 integrin signaling, leading to changes in endothelial cytosolic free calcium and reorganization of actin filaments [ 1].
Nod2 is important in the maintenance of intestinal epithelial integrity as has been shown by increased intestinal permeability (Barreau et al., 2007; Barreau et al., 2010) in Nod2 KO mice.
In addition to influences on dendritic integrity, VPA treatment has been shown to enhance hippocampal neurogenesis [45].
β-actin is involved in cell motility, structure, and integrity, whereas ef1 has been shown to play a central role in protein synthesis in teleosts (Jurss et al. 1992).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com