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In conclusion, these data identifies NPY as a critical integrator of bone homeostatic signals; increasing bone mass during times of obesity when hypothalamic NPY expression levels are low and reducing bone formation to conserve energy under 'starving' conditions, when hypothalamic NPY expression levels are high.
These results indicate that FGF21 is a negative regulator of bone turnover and a key integrator of bone and energy metabolism, and underscores the importance of the whole body energy metabolism in bone physiology.
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We conclude that Lrp4 is a novel osteoblast expressed Dkk1 and sclerostin receptor with a physiological role in the regulation of bone growth and turnover, which is likely mediated through its function as an integrator of Wnt and BMP signaling pathways.
Bone mineral density, estimate of bone mass.
A piece of bone".
Shares in Nomura Research, Japan's largest integrator of computer systems, hit 14,050 yen ($110) a share.
The Mediator complex: a central integrator of transcription.
After all, the Soviet Union was the great negative external integrator of Western Europe for 40 years.
You mocker of reality, you banisher of depth, you integrator of products, you destroyer of souls.
"It's the exploration of sort of a new world," said Doug Powell, chief integrator of Maiden Lane, an advertising agency.
We present nigo, a Numerical Integrator of Galactic Orbits.
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