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In both samplers, the uptake of selected analytes was integrative over exposure periods of up to 384 h.
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Hence, we were unable to find evidence pointing to advantages of integrative treatment over acupuncture alone.
Larger and longer term studies are needed to evaluate the added value of the integrative treatment over therapeutic acupuncture alone.
Ontologies are used in biomedicine to standardize terminology, to enable access to domain knowledge, to verify data consistency and to facilitate integrative analyses over heterogeneous biomedical data.
Key Points Ontologies are used in biomedicine to standardize terminology, to enable access to domain knowledge, to verify data consistency and to facilitate integrative analyses over heterogeneous biomedical data.
Larger and longer term studies are needed to evaluate the added value of the integrative treatment over therapeutic acupuncture alone and in relation to usual care practices in primary care.
Longitudinal analysis revealed an increase in integration capacity betweeen week 30 and week 40 (P = 0.0286, Fig. 6), supporting the notion of a growth of the connectome toward a more global and integrative network over time.
It may also be speculated that outcomes favoring acupuncture and integrative treatments over conventional care owe to a care effect, i.e. better outcomes resulted from patients receiving more frequent care independent of treatment regimen.
Ontologies are now pervasive in biomedicine, where they serve as a means to standardize terminology, to enable access to domain knowledge, to verify data consistency and to facilitate integrative analyses over heterogeneous biomedical data.
The spill-over effect implies a gradual delegation of functions from the national to the supranational level taking place as a result of the functional spill-over creating integrative pressures in one policy area through integration in another, and the political spill-over shifting the level of attention from the national to the supranational level.
Interest in this type of formulation strengthened during the period when molecular biology began to take over from integrative physiology as an explanatory approach in biological sciences.
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