Sentence examples for integrative cluster from inspiring English sources

The POLE mutation data for EC was extracted using the "Integrative Cluster" information provided by the original study [ 27].

Gene expression data was available for further 1974 clinically annotated patients with PAM50-based subtype definition and integrative cluster group assignment (METABRIC, (Curtis et al, 2012)).

Additionally, we hypothesized that the combined assessment of PPP2R2A and Cyclin D1 protein expression would further refine the subgroups' outcome associations and be potentially useful in identifying Integrative Cluster 2-like BC.

Moreover, approximately half of the cases with the PPP2R2A-/low/Cyclin D1high phenotype correspond to luminal B-like BC, which is similar to the prevalence of luminal B BC in Integrative Cluster 2 BC [ 12].

We did not include the classification for molecular subtype proposed by Curtis et al. [ 46] as the IC (Integrative Cluster) subgroups are based on clustering on both gene expression and copy number data through a joint latent model [ 56].

Individual genes shown in Figure  9 C are depicted with significant survival differences with low (green) versus high (red) gene expression for both integrative cluster (IntClust) breast cancer subtype groups and PAM50 subtypes.

This stratification of breast cancers into integrative clusters reveals prototypical patterns of single-nucleotide variants and is associated with distinct clinical courses and response to therapy.

The realization that a significant proportion of the gene expression landscape is determined by the somatic copy number alterations that drive expression in cis led to the newer classification of breast cancers into integrative clusters.

The algorithm is an integrative clustering and selection algorithm.

In addition to the individual dataset clustering, we performed integrative clustering.

In other words, integrative clustering relies on joint structure across datasets, rather than individual dataset structure.