Sentence examples for integration preferences from inspiring English sources

Bound transcription factors may very well be the cellular mediators of the LTR-associated component of RV integration preferences.

On the contrary, similar LTR modifications (ΔU3-HIV[CMV], ΔU3-HIV[MLV] and MLV-HIV) had no apparent consequence on the LV integration preferences (Figure 1).

Different retroviruses show significantly different integration preferences [2] [4], implying that PICs recognize components or features of the host cell chromatin in a specific fashion [5] [7].

It has recently been suggested that HIV-derived LV vectors, due to their different integration preferences and LTR enhancer-free design, could be associated to a lower genotoxic risk compared to conventional RV vectors [14], [25], [38], [39].

Based on the annotation reported in Figure 1, we generated seven weighted control groups of random sequences that reproduce, in proportion, the integration preferences of each vector set (Table S1).

HIV proviruses are instead preferentially associated to histone modifications extending throughout the body of active genes (H4K12ac, H2BK5me1, H3K27me1, H3K36me3, and H4K20me1), consistent with the integration preferences of lentiviral vectors [22], [28].

The deep sense of community and always-connected lifestyle that has resulted in their work-life integration preference is why millennials measure productivity by work completed, not by time spent on a task -- especially not time spent in the office.

Besides, T-DNA exhibits certain integration preference and may therefore not saturate the entire rice genome [8].

Whereas no ISAba1 copy was identified on any of the plasmids of isolate AYE, chromosomal copies showed no site integration preference (Figure 3).

Understanding the integration preference sites for each respective class may shed light on the order of integration events.

The Sleeping Beauty transposon has the most random integration preference of the vectors currently in use for gene therapy [ 30, 31].