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Integration of retrotransposition events is random.
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This assumes that the mechanism of retrotransposition do not lead to truncated copies upon integration.
This suggests that the first-step integration via the retrotransposition of intron is very important to increase the chance for the following homologous recombination.
In O. alta, Atlantys proliferation events postdated its speciation thereby constituting an example of retrotransposition activation that could have been induced by "genomic shock" [34] during polyploidization.
However, the interpopulation Pi value was greater than any of the single populations, again confirming that the timing of retrotransposition events primarily occurred after speciation (Table 4).
Any particular element may be present in all the species but due to varying rates of retrotransposition may amplify only in one or a few species.
Given the unique TPRT mechanism of LINE-1 retrotransposition, where integration and reverse transcription occur in concert, we cannot rule out the possibility that in the presence of nRTIs the frequency of initiation of retrotransposition remains unchanged, while the length of de novo insertions is compromised by inhibition of the RT enzyme.
There is ample precedent for periods of retrotransposition associated with species-specific genome expansion in angiosperms.
Assuming that high levels of retrotransposition are detrimental to the host, selection will favour regulation of retrotransposition.
These pseudogenes are likely the products of retrotransposition of the LIN28 transcript following RNA splicing.
This scenario is supported by recent experiments of retrotransposition assay of eel UnaL2 and human LINE1.
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