As a gene may be regulated by both TFs and miRNAs, integration of the regulation relationship between TFs and their target genes into the database will give more insight into the combinatorial regulation of miRNAs and TFs to their common target genes.
In fact, integration of potassium regulation with glucose control was very effective with marginal extra costs or time spent [29].
The study of splicing is moving from focused attention on the regulatory mechanisms of a selected set of paradigmatic alternative splicing events to questions of global integration of splicing regulation with genome and cell function.
Our results suggest a further integration of this regulation component into current cloud management platforms in order to open them up for the operation of an ecosystem of collaborative cloud services in community networks.
The decrease in specific components is being driven partly by integration of new regulations and standards for on-road heavy-duty diesel engines and off-road regulations stretching out to 2016.
Overall, this general theme points to a psychologically healthy life as a state of integration: Of self-regulation of emotions; cognitive focus, moment-to-moment; values, attitudes and behavior that support wellbeing in both yourself and others; and physical-dietary practices that are linked with them.
The integration of transcription regulations and protein-protein interactions gives more insight into actual biological networks and it is more predictive than those without integration [ 77].
The integration of transcription regulations and protein-protein interactions gives more insight into the actual biological network and is more predictive than those without integration.
Different findings indicate that rostral ventrolateral reticular nucleus (RVL) is neuronal substrate of integration and regulation of the cardiovascular functions.
The major advantage of our reformulation is its easy integration of (binary) transcriptional regulation.
As reviewed in detail by Gonçalves et al. [ 147], bridging layers towards an integration of signal transduction, regulation and metabolism into mathematical models still posts many challenges as each of the biological layer has their own distinct characteristics and therefore is suitable for only a subset of modelling approaches.
