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One example of deeper integration dates back to 1992.
Point estimates of integration dates are hard to find in the literature, except for the more recent ERV-K group.
Using the basic phylogenetic data to infer integration dates, we obtained point estimates of integration time for each endoretroviral sequence.
With the GRD integration dates in hand we attempted to determine the tMRCA of the OW and NW begomoviruses using BEAST.
It must, however, be emphasised that these most probable estimates of the dates when the OW-NW begomovirus split occurred (i.e. 29.6 and 20.3 MYA) were derived considering only the most probable integration dates of the two GRD elements (i.e. the median estimates of these integration times).
Whereas the contemporary OW and NW begomovirus sequences used in these analyses were given sampling dates of 0 time units ago, those of the GRD sequences were given sampling times corresponding to the median, 95% upper and 95% lower highest probability density (HPD) intervals of the GRD3 and GRD5 integration dates.
Similar(53)
Considering the upper and lower 95% HPD bounds of the integration date estimates, the plausible interval within which the OW-NW begomovirus split may have occurred was between 4.6 and 78.2 MYA using the "neutral rate" approach estimated dates and between 2.9 MYA and 40.3 MYA using the "Nicotiana phylogeny" estimated dates (Figure 3).
While the first psychophysical and computational models of visual integration date back to the pioneering work of Gestalt psychologists, it is only recently – with the advance of neuroimaging tools – that the neural signature associated with global form perception has been investigated in humans.
Since two LTRs of a single LTR retrotransposon have identical sequences at the time of integration, dating the transposition event of a LTR retrotransposon can be achieved reliably by computing the sequence similarity of its two LTRs [ 13].
Third, "poke and push courtship" behaviors did not influence peer group integration or dating.
The Integra Initiative (Integra) is one of the largest studies evaluating service integration to date, including twenty-four public and six private health facilities in Kenya, and eight public and two private health facilities in Swaziland.
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