Sentence examples for integration complex from inspiring English sources
Nevertheless other aspects such as technology may make integration complex, for example, when integrating RNA-seq and microarray based mRNA profiling.
Conventional analysis methods for building structures with added viscoelastic dampers, such as direct integration, complex mode superposition, and modal strain energy method, were compared, and a procedure based on rigid diaphragm assumption and matrix condensation technique was proposed for application in the preliminary analysis and design stages.
But while building that first version of the service, the team quickly realized that all of the APIs it was trying to work with were quite different from each other, which made their integration complex and time-consuming.
Although this value for k3 is appropriate in the simulations using in vitro parameters, it would be unrealistically short in an in vivo situation where the integration complex must be disassembled and the empty donor site restored.
Several cellular DNA binding proteins have been described that bind integration complexes and/or facilitate integration, including BAF, HMGa1, Ku, and LEDGF [4], [14].
A byproduct of the process by which the HIV pre-integration complex enters the nucleus and gives rise to an integrated provirus is the formation of 2-LTR circles.
Nuclear entry is a selective, dynamic process granting the HIV-1 pre-integration complex (PIC) access to the chromatin.
This characteristic is due to multiple karyophilic components of the lentiviral vector pre-integration complex.
Arhel, N. J. et al. HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore.
After infection of cells, WT IN (gray circle) and labeled IN (green circle) associated with reverse transcribed vDNA are imported into the nucleus assisted by TRN-SR2 as part of the pre-integration complex (PIC).
After reverse transcription of the viral RNA into double stranded DNA, the pre-integration complex (PIC) is formed as an assembly of the viral DNA (vDNA) and cellular and viral proteins.
