Sentence examples for integrated variants from inspiring English sources

Additionally, integrated variants were required to represent a minimum of 60% of the alignment data.

The seminal work of (Barabási and Albert, 1999) directed complex networks research toward revealing the unifying properties of biological networks, starting from metabolic (Jeong et al., 2000) to gene regulatory (Shen-Orr et al., 2002) to protein protein networks (Maslov and Sneppen, 2002) and their integrated variants (Yamada and Bork, 2009).

Here, we merge publicly available whole genome sequence data of 40 widely used rat inbred strains and substrains into a comprehensive integrated variant inventory.

Genotypes were imputed using the 1000-Genomes Project as the reference panel (Phase 1, integrated variant set across 1092 individuals, v2, March 2012) using the MaCH and minimac software packages.

Imputation was performed with IMPUTE2 version 2.2.2 [ 78, 79] using the 1000 Genomes Phase I integrated variant set release (v3) (https://mathgen.stats.ox.ac.uk/impute/impute_v2.html) [ 51] as reference panel.

Imputation was performed using the IMPUTE 2.0 software package (https://mathgen.stats.ox.ac.uk/impute/impute.html) using haplotype information from the 1000 Genomes Project (Phase 1, integrated variant set across 1092 individuals, v2, March 2012).

We imputed the 4p16.1 region (from 9900 to 10400 kb) based on 9172 samples and 260 typed SNPs in ARIC using IMPUTE2 (56) and the 1000 Genomes Project reference panel (phase1 integrated variant set v3).

Imputation using the multi-ethnic 1000 Genomes Phase I integrated variant set (release v3) 'ALL' reference panel (55, 56) was done following guidelines from the GIANT consortium (http://genome.sph.umich.edu/wiki/IMPUTE2:_1000_Genomes_Imputation_Cookbook).

Imputation was performed spanning the hg19 chromosomal coordinates chr15:85,275,210–85,494,027 with the results of targeted sequencing experiment as a reference panel along with the 1000 Genomes Project Phase I integrated variant set.

SNP genotypes were acquired from the chromosome 6 integrated Variant Call Format (VCF) file from version 3 of the 1000 Genomes Project Phase I data, which is available at ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/release/20110521/ (The 1000 Genomes Project Consortium 2012).

An additional 6.4 million SNPs with frequency ≥0.01 were imputed with high fidelity (info-score ≥90%) using the 1000 Genomes Phase I integrated variant set release v3 and the IMPUTE v.2.2.2 software [ 23].