The U.S. Global Health Initiative calls for both "upstream" and "downstream" integration to coordinate and integrate health interventions [ 1].
How the activities of the numerous actin regulators known to operate in hemocytes are integrated to facilitate coordinated cell migration will doubtlessly be an important area to watch.
The crucial next steps are to discover how newly associated signals and cellular processes contribute to the mechanism of differentiation and, in particular, how signalling and cell cycle regulation are integrated to promote coordinated epigenetic changes that re-configure chromatin for neural differentiation.
However, provision of care needs to be coordinated and integrated to meet the individual needs and health concerns.
nocoRNAc incorporates a set of protocols for the detection of transcriptional features which are then integrated to determine the sRNA transcript coordinates.
Multiple signaling pathways converge on skn-1, which integrates these signals to coordinate appropriate responses to ageing, insulin signaling, caloric restriction, and oxidative stressors [43], [44], [45], [46], [47].
To put it differently, in order for the massively embedded, distributed, networked devices and systems, which are invisibly integrated into the environment, to coordinate require middleware components, architectures, and services.
The additional DE genes for receptors in the dCIN population reflect the fact that dCINs integrate various synaptic signals to coordinate left-right movement during locomotion.
Motivation: Protein complexes integrate multiple gene products to coordinate many biological functions.
The question of how IL6 integrates multiple signalling cascades to coordinate nutrient homeostasis in mammals remains unanswered.
