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In conclusion, our study demonstrates that XAGE-1b acts as a genuine tumor antigen eliciting integrated systemic and/or tumor-infiltrating antigen-specific humoral and cellular immune responses in Caucasian patients with pulmonary adenocarcinoma.
However, available evidence supports the concept of integrated systemic and mucosal immune systems.
We observe that effective global mechanisms for integrated systemic risk governance are often inadequate or lacking.
It should help bridging the gap between East and West in the common pursuit of integrated systemic risk governance and capacity development.
We recommend that the Global Risk Forum Davos (Shenzhen Qianhai) focus on integrated systemic risk governance in an increasingly globalized world.
This study empirically investigates the supplier orientation, supplier dependency, customer orientation, and integrated systemic buying that influence a company's supply risk management performance.
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Cross-sectoral impacts would also be associated with an educational reform across the EU in order to integrate systemic approaches to problem solving and to ensure basic education about all aspects of sustainability [19].
Standard treatment approaches integrate systemic chemotherapy, surgery, and radiotherapy [ 1].
The optimal combination of systemic therapy and local therapy is yet to be determined and a few clinical trials integrating systemic therapy with SABR are ongoing.
The stem cell niche refers to a well-defined physiological compartment that includes cellular and acellular components and serves to integrate systemic and local signals to regulate the biology of stem cells (reviewed in [ 1, 2]).
A proper environment for the application of quality management could be achieved through an integrated multi-systemic quality and safety management model on a port authority level.
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