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Recent work has integrated roles for both protein signalling and lipid modification in natural membrane fusion [1], [2], [3], [4], [5].
Taken together, results of previous studies have suggested integrated roles of large body size and physiological and behavioral adjustments in leatherback thermoregulation.
Although ErbB-2 overexpression alone cannot transform cells (Ross and Fletcher, 1998), it has highly integrated roles in cellular signalling that impact on the classic 'hallmarks' of cancer (Hanahan and Weinberg, 2000).
The results of our screen demonstrate that mitochondrial function, vesicular sorting, EGO-GSE/TORC1 amino acid signaling, and the retrograde response have integrated roles in regulating ATP efflux from S. cerevisiae.
The recent identification of genes encoding some of these transport systems has allowed new studies toward further understanding of their integrated roles in plant.
Due to the successful application of the newly developed Lifeact probe for live-cell imaging of F-actin it is now possible, in combination with existing microtubule markers and fluorescently labelled septins, to monitor real-time dynamics of the entire fungal cytoskeleton, and reassess the many and integrated roles of F-actin, microtubules and septins throughout fungal growth and development.
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Moreover such an additional, but now integrated, role structure participates in, and influences the direction of, the institution; it is now a contributing element to the momentum of the institution.
Cytokinins play a diverse and highly integrated role in plant growth and development, but are traditionally considered compounds that promote cell division and growth [ 19].
Information technology has opened up opportunities to improve the systems that support the medical home's integrated role in newborn screening and there is always the opportunity to improve informatics and communications and their integration into public health information systems and registries.
Comparing the set of interactions mediated by these three positions (153, 160 and 188) for canonical and HNF4's DBD HRE interactions we can suggest an integrated role for these three residues at the HNF4 positioning on it divergent half-site.
A direct relationship between ATM with other metabolic or nonmetabolic disarrangements suggests that ATM plays integrated role that goes beyond local AT inflammation [ 48], with emphasizing on the effects of polarization state of ATM on systemic inflammation and insulin action [ 49, 50].
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