However, because vascular tone reflects an integrated response to a variety of signals that vary in importance among vascular beds (Cornelissen et al. 2002; Hill et al. 2001; Zweifach 1991), our finding that arteriolar tone is unaltered after PM exposure is not necessarily at odds with the observations of Brook et al. (2002).
For example the sRNA RybB has been shown to regulate sodB, ftnA, bfr, acnA and sdhC and thus acts as a regulatory node allowing a complex and integrated response to a given growth condition, in this case low iron concentrations [20].
In vivo response: integrated response to a (standardised) in vivo challenge (e.g. response to vaccination, prick and patch tests or oral provocation test).
It cannot be excluded that each pathway alone and/or as an integrated response altogether was responsible for the seemingly mixed physiological changes observed in HR, FMD, and BAD.
In a binary logistic regression model comprising all tested markers as covariates and the integrated response score as a dependent variable (all dichotomised as indicated), only the Ki-67 score was independently associated with response (P=0.04).
More funds are urgently needed reflecting the increasing needs to expand a fully integrated response to the nutrition crisis, a deteriorating emergency in Mali and an upsurge of cholera and other epidemics across the region.
This work shows that MSCs induce an integrated response to liver disease and further lays a solid foundation for application of MSCs in the treatment of this devastating disorder.
In this review manuscript we will discuss autophagy as part of an integrated response triggered in TM cells in response to strain, exerting a dual role in repair and mechanotransduction, and the potential effects of dysregulated in outflow pathway pathophysiology.
But, he said at a joint news conference in London with Prime Minister Gordon Brown, the nature of the crisis demanded an integrated response.
It will also trial an "integrated response model" to better coordinate help for victims in one urban, one regional and one Indigenous community.
