Sentence examples for integrated randomly from inspiring English sources

Thus, the two T-DNA cassettes were integrated randomly as independent loci into the tobacco genome.

On the assumption that the hygromycin B phosphotransferase gene (hph) was integrated randomly into the genome of A95, total genomic DNA of the transformants was amplified with the primer pair hphRforw (5'-ATGCCTGAACTCACCGCGAC-3') and hphRrev (5'-CTATTCCTTTGCCCTCGGACGAG-3').

Such high efficiency may be caused by 1) all the hpRNA constructs targeting an exon sequence but T-DNA or Tos17 integrated randomly in chromosomes and 2) hpRNA possibly causing the silencing of a gene family instead of only a single gene.

Histology showed that cells integrated randomly into the tissue without specific distribution.

PCR was performed on the transformants generated on potato disc, which confirmed presence of both the hph and DsRed genes in all transformants (see Figure 1), and Southern analysis demonstrated that as with conventional ATMT of V. albo-atrum [16] T-DNA integrated randomly into genomic DNA, and as single copy insertions (Figure 2).

Three copies of the BAC integrated randomly into the genome.

Assuming that transposons should re-integrate randomly across the genome, we calculated the expected frequency of integration events for each chromosome based on what proportion of the genome each chromosome represents in Mb.

However, because injected neural stem cells integrate randomly into the host neural network, another approach is needed to establish a neural pathway between selective areas of the brain or treat widespread degeneration across multiple brain regions.

Insertional mutagenesis has emerged as a major obstacle for gene therapy based on vectors that integrate randomly in the genome.

Insertional mutagenesis has therefore emerged as a major obstacle for gene therapy based on vectors that integrate randomly in the genome [10], [11].

Gamma-retroviruses favor integrations near TSS and CpG islands, lentiviruses integrate preferentially within active transcription units, while alpha- and beta-retroviruses, such as the avian sarcoma-leukosis virus and the murine mammary tumor virus, appear to integrate randomly into their host cell genome [4], [37].