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Although HbA1c remains the best validated, integrated measure for blood glucose currently available, the accuracy and utility of HbA1c measurement can be impacted by several issues.
Validating an exposure pathway model is difficult because the biomarker, which is often used to evaluate the model prediction, is an integrated measure for exposures from all the exposure routes and pathways.
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Studies of hormone disruption would be strengthened by integrated measures for hormonal activity to augment measurements of individual chemicals, an approach currently hampered by lack of knowledge about what chemicals might affect a given pathway and to what degree.
However, a lack of integrated measures for biodiversity has greatly constrained the national and international response to the biodiversity crisis.
Arsenic concentrations in finger nails and hair have been reported to provide the integrated measures for arsenic exposure [ 26, 27].
Arsenic levels in nail and hair samples have been reported to provide the integrated measures for arsenic exposure [ 29, 30].
These findings suggested that while border measures are established to mitigate the triggering of a dengue outbreak, integrated measures for reducing the transmission of mild, latent and asymptomatic viremic carriers of dengue and preventing the spread of secondary domestic infections should simultaneously be enforced.
Desirable as well would be a more integrated measure of quality for the next occurrence of the disaster.
An integrated measure of expression for frequency and intensity of staining was calculated using the following formula: [3(%x)+2(%y)+1(%z)]/100, where x, y, and z represented the percentage of cells staining at intensity 3, 2, and 1, respectively.
The PETiT scale offers a specific and integrated measure of HRQoL for patients who have switched antipsychotic medications, where a patient's well-being is conceptualized as their subjective perception of their severity of psychotic symptoms, medication side effects, and level of psychosocial performance [ 28].
Motivated by the need to develop an integrated measure of simplicity perception for a smartphone user interface, our research incorporated visual aesthetics, information design, and task complexity into an extended construct of simplicity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com