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In line with previous studies in other cell types, mechanistic in vitro studies revealed an integrated interplay between αv integrin and TGF-β, a strong driver of invasion and metastasis of breast cancer.
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This necessitates a smoother, better-integrated interplay between the functional roles of planning and operations to leverage the capabilities of probabilistic analysis in both realms.
Understanding plasma/complex surfaces interactions in NSTX with liquid lithium on thin porous molybdenum substrate for the divertor, additional PFC surfaces such as carbon tiles, and the presence of gases and impurities require integrated implementation and the interplay of detail various physical processes.
Specifically, the mitochondrial impairment integrates the close interplay of the two common hallmarks of AD, plaques and NFTs, or Aβ and tau, which act independently as well as synergistically on this vital organelle.
The fatty acid (FA) profile of blood and tissues integrates the complex interplay between dietary intake of FAs and endogenous FA metabolism, and has been shown to be associated with risk of type 2 diabetes in a number of studies [ 1– 6].
This fully integrated model resolves a complex interplay between heat transfer at the macroscale and grain structure evolution and microsegregation formation at the mesoscale.
These cycles usually form metabolic hubs where many functionally distinct pathways are integrated; an analysis of the interplay between supply and demand around these cycles is crucial for our understanding of metabolic regulation.
Although operationally independent, the biochemically integrated GABAergic and glutamatergic neurotransmitter systems do interplay at cellular and sub-cellular levels [1] [6].
This study highlights the complexity of the inactivation process and is a crucial step towards creating a module of equations describing the PC pathway that can be integrated into existing comprehensive mathematical models describing the interplay between procoagulant and anticoagulant processes during tissue factor initiated coagulation.
Their proximity to each other in activities in the IPEICU initiated and refined a collaborative interplay were they drew on, negotiated and integrated their individual and common experiences concerning the patients' problems into a shared understanding.
Complexity stems from the interplay among levels of biological organization as energy and matter is integrated into larger units that superimpose onto the smaller parts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com