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Absolute metabolic fluxes and metabolite levels give detailed, integrated insight into the physiology of this industrially, medically and agriculturally important bacterial species and suggest that the most efficient way of using a mucA- mutant as a cell factory for alginate production would be to use non-growing conditions and nitrogen deprivation.
When applied in research, this means that, rather than just showing how depressive symptomatology can be decomposed into symptom domains or showing how a sample can be decomposed into subtypes based on symptom profiles, 3PCA provides a more integrated insight into how persons differ in terms of their course-trajectories on different symptom-domains.
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What experimental designs are required to yield truly integrated insights?
The integrated sensing technique provides insight into the stamping process by quantifying process variations and providing a reference base for process control to reduce product disparities.
Using such an integrated approach would provide insight into the predictive value of preclinical animal models.
This critically stable damping provides new insight into the integrated design of control and structure.
Understanding HMGB1-dependent and -independent autophagy in more detail will provide insight into the integrated stress response and guide HMGB1-based therapeutinterventioninn in cancer and other diseases.
In this study, we took an integrated approach to gain new insight into the metabolic, energetic and photosynthetic lifestyles of R. sphaeroides.
Understanding HMGB1-dependent and -independent autophagy in more detail will provide insight into the integrated stress response and guide HMGB1-based therapeutinterventionintervention
Our model therefore shows the complexity of the interaction between the two pathways and highlights the need for such integrated computational models to give insight into the dysregulation of insulin signalling along with more data at the individual level.
We are using an integrated approach to gain more insight into what might occur when the airway mucus-cilia unit is exposed to novel agents that selectively raise elasticity relative to viscosity of one of the components: the mucus macromolecule.
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CEO of Professional Science Editing for Scientists @ prosciediting.com