So, we propose a framework in three levels for optimizing a waste minimization program: an integrated improvement process (level 1), a strategic matrix and an integrated toolkit (level 2), and finally an "advanced 3R (Reduction / Reuse / Recovery)" method (level 3).
The Ministry of Agriculture funds biogas construction in Sichuan through the integrated improvement of kitchens, latrines and livestock sheds.
When we calculated the average absolute improvement in prediction of risk without categorisation into risk groups, the integrated improvement in discrimination was 0.0022 (0.0010 to 0.0033; P<0.001).
We compared the predictive powers of AAs and conventional risk factors for risk of diabetes using the net reclassification index (NRI), the integrated improvement index (IDI) and Harrell's C statistic [ 23, 24].
The need for additional analyses, i.e. measures of discrimination improvement (integrated discrimination improvement, IDI, and net reclassification improvement, NRI) will be decided for each marker separately.
Alternatively, the net reclassification improvement and integrated discrimination improvement integrate sensitivity, specificity, and the information from reclassification tables to assess improvements in risk models that include new risk factors (23).
The machine learning algorithm and traditional regression analysis models had similar c-statistics using ROC curve analysis, but the machine learning algorithm, using random forest, outperformed the traditional regression model when using net reclassification improvement, integrated discrimination improvement, and misclassification tables.
Reclassification analyses (net reclassification improvement (NRI), integrated discrimination improvement (IDI), and category-free net reclassification improvement (cfNRI)) were used for the characterization of improvement of standard TIMI and GRACE risk scores by the addition of new markers and for the comparison of multivariate models with and without PTX3.
Whether net reclassification improvement and integrated discrimination improvement are indeed more sensitive than the C statistic to detect small improvements in discrimination remains largely unknown thus far.
The effect of eGFR on reclassification of risk was assessed using net reclassification improvement and integrated discrimination improvement [ 22, 23].
