IDAAPM aims to bridge the gap by providing, in a single resource, integrated detailed information on approved drugs (small molecules and biologics) such as FDA application data, structures, molecular descriptors, ADMET properties and adverse effects, target and also related bioactivity data that are often missing in other comparable databases.
In this study, we integrated detailed drug data with predicted candidate genes for seven complex diseases.
DrugBank integrates detailed chemical, pharmacological and pharmaceutical drug data with target information.
The study integrates detailed lithofacies analysis based on vertical and lateral profiles, in addition to thin-sections petrography to reveal the high-resolution architecture framework.
In these circumstances, quantitative mathematical modeling is an essential tool, both to integrate detailed knowledge of individual transporters and to extract the properties emergent from their interactions.
This work integrates detailed geological and hydrogeological information with PSI data to obtain a better understanding of subsidence processes detected in the detrital aquifer of the Vega de Granada (SE Spain) during the past 13 years.
The Centre for Ecology and Hydrology (CEH), in the UK and the EU, is addressing the issues of environmental data collection at a range of different scales, creating a structure to integrate detailed field-based measurements with information from remote sensing.
The aggregation of data on the H1N1pdm therefore represents an unprecedented opportunity to calibrate and validate a modeling approach to the global spread of epidemics that integrates detailed information on human mobility and travel.
An alternative, 'pragmatic science' approach by Berwick [ 47] promotes tracking effects over time, integrating detailed process knowledge into the work of interpretation, using small samples and short experimental cycles of change, and using multifactorial designs in evaluating system change.
Integrating detailed information regarding the specific type of IE, comorbidities, hospitalisation, activities of daily living (ADL) and level of physical activity prior to IE, the physiotherapist conducts a patient consultation of up to 30 min.
Here, I integrate detailed climate change scenarios for the two most significant Africa-wide mosquito vector species based on ecological niche models and detailed spatial summaries of present-day human population distribution [ 29, 30] to calculate shifting patterns of potential human exposure to malaria across Africa to be expected over the coming half-century.
