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We observed several differences between the integrated data set incorporating all genomic features versus an analysis of individual genomic feature data set (e.g. mutations alone, copy number alone, etc).
We averaged the three normalized data sets to obtain an integrated data set.
We have established that CHESS addresses the problem of seamless data integration across multiple sources of information by demonstrating a query that reproduces a common Rule of Five filter, on an integrated data set from three different sources.
We combined these three published data sets [1] [3] to form an integrated data set consisting of 7,570 distinct highly conserved elements (HCEs) in the human genome, and used BLASTn with non-stringent parameters plus order and distance conservation criteria to locate all occurrences of the same HCEs in the mouse, rat, chicken, zebrafish and tetraodon genomes (Materials and Methods, Figure S2).
Using this integrated data set, we first identified CpG loci with a linear relationship with age.
The integrated data set from the maternal and paternal maps allowed construction of a consensus linkage map.
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"Companies and developers can… use Digi.me's APIs to request access to integrated data sets to provide better data-driven experiences, services, and rewards, and to provide other benefits like rich personal analytics.
Essentially only the organism-specific databases and web sites allow some access to integrated data sets.
In order to retrieve information of miRNA targets in rhesus monkeys, we integrated data sets of different sources.
SM implemented the design, developed the database from integrated data sets, and implemented the web-based database interface.
Such integrated data sets have been used to study a range of health issues to identify risk and protective factors and to examine outcomes.
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