Sentence examples for integrated at random from inspiring English sources

The transgenic events derived by these methods carry the transgenes that are integrated at random sites in the plant genome.

TRIP allows for simultaneously analyzing the quantitative readout of numerous sensor constructs integrated at random locations in the genome.

Expression cassettes were integrated at random in Y. lipolytica genome in single copy as described previously [ 49, 51].

rAAV-mediated gene targeting vectors can also integrate at random locations (2).

Since MMTV integrates at random into the nuclear genome, clones derived from individual infected mammary epithelial cells could be distinguished.

It has the natural ability to transfer a segment of DNA from its Ti plasmid, known as 'T-DNA' into plant or fungal cells so that the T-DNA integrates at random into the nuclear chromosomes [ 5- 7].

Analysis of regulatory sites within Alus suggests that a polymorphic Alu has the potential to transpose and recombine which allows it to integrate at random sites in the genome.

Therefore, it may be worthwhile revisiting some of these experiments (especially those involve cAMP pathway or cytokine signaling) using the new-generation cre transgenics such as the 'self-excising cre' or using the ROSA-Cre system where CRE-ERT2 is integrated at the rosa26 locus, which eliminates random integration effects and the effect on the PKA pathway by regulated administration of 4-OHT.

Another result in favor of the open chromatin interpretation is that "new" Alu sequences integrate essentially at random in the genome, but this happens in the paternal germ line [43] [45], where open chromatin is much more widespread over chromosomes.

Insertional mutagenesis was carried out using the parental parasite line described above with a vector that integrates at random, followed by bradyzoite induction in vitro and negative selection to isolate differentiation mutants.

Recently, it has been shown that the transposase piggyBac integrates at random into the genome of the human malaria parasite P. falciparum offering the possibility to develop forward genetic screens to analyse Plasmodium gene function.