Sentence examples for integrated and silenced from inspiring English sources

The tumors that tested negative for luciferase activity included the six tumors that tested negative for the presence of the luciferase gene, suggesting that the luciferase donor plasmid was not integrated and silenced in these tumors.

Data were integrated and reduced using HKL2000 [21].

The CRISPR/Cas system is a defense mechanism that relies on the ability to integrate foreign DNA into genomes, so that future invaders can be recognized and silenced or degraded (Grissa et al. 2007; Terns MP and Terns RM 2011).

PCR on genomic DNA confirmed that the selection cassette was not re-integrated in a silenced form elsewhere in the genome (supplementary material Fig. S5F).

In plants, miRNA biogenesis follows a similar process, but a miRNA seems to be fully matured into a single stranded miRNA before being exported to the cytoplasm and integrated onto the silencing complex, which partially explains why intermediate forms of plant miRNAs are only rarely detected [ 9, 17].

It was silence then and silence now".

We have discovered that stably integrated Ptet becomes functionally silenced in the majority of neurons when it is inactive during development.

This is not terribly satisfying, as integrated arrays can be silenced to different degrees.

They are processed by specific complexes of proteins containing Drosha and Dicer and integrated into RNA-induced silencing complexes.

Thus, EZH2 integrates the epigenetic silencing of miR-205 and miR-31 to confer resistance to chemotherapy-induced apoptosis.

Mature miRNAs are then transported to the cytoplasm and integrated into the RNA-induced silencing complex (RISC) [7,8].