Sentence examples for integral role in normal from inspiring English sources
Its main function is to produce the cerebrospinal fluid (CSF) that plays an integral role in normal brain function and development as well as in recovery from injury [1], [2].
VEGF has been shown to have an integral role in normal haematopoiesis with autocrine signalling required for both survival and growth of HSCs.
Estrogens and their receptors, including estrogen receptor-alpha (ER-alpha) and estrogen receptor-beta (ER-beta), play an integral role in normal growth, differentiation, and development of the prostate.
Functional studies have demonstrated that these genes play an integral role in normal cellular processes, including cell proliferation, death, survival, stress response, motility, differentiation, crosstalk between cells, and tissue architecture, indicating that cancer arises from dysregulation of normal cellular processes.
PI3K signaling plays an integral role in many normal cellular processes, including survival, proliferation, differentiation, metabolism and motility, in a variety of cell types [ 53].
While it is possible to reduce the volume of ER+ tumors by inhibiting the production of estrogen it is important to consider that estrogen plays an integral role in the normal physiology of women by controlling diverse processes such as cholesterol production and maintenance of bone density [ 6].
Pharyngeal motor cortex plays an integral role in the control of normal swallowing function, and other neurostimulation techniques have shown that stimulation of pharyngeal cortex is able to improve dysphagia following stroke (7, 21, 40).
EMT and MET comprise the processes by which cells transit between epithelial and mesenchymal states, and they play integral roles in both normal development and cancer metastasis.
Potentially high tau levels may predict ER-positive tumours with increased sensitivity to endocrine therapy, whereas low tau levels may distinguish ER-positive tumours more chemosensitive to taxane therapy [ 50]. p53 is a critical tumour suppressor playing an integral role in cellular apoptosis and regulation of normal cell growth.
Thus, bending-related normal faults may play an integral role in near-trench subduction zone processes.
Establishment of normal routine is an essential step, and UNICEF played an integral role in ensuring that all children could return to school in October 2006, just two months after the war had ended.
