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An integral requirement of the CRISPR/Cas system is that the target site be followed by a protospacer adjacent motif (PAM).
We suggest that commissioners and providers should give high priority to ensuring that implementation of such a programme becomes an integral requirement for safe antenatal care, and is monitored by antenatal detection rates of fetal growth restriction as a key indicator of the quality of the service.
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The established novel chrome tanning process satisfactorily solves the longstanding problems commercially and matches the integral requirements of the modern sustainable leather industry.
This means that the medical devices first used in critical and high dependency care units are now integral requirements in the delive ry of direct patient care in acute ward areas.
Rail will have to re-position itself to this either by re-investment and the re-commissioning (e.g. being done in the UK) of such links or advocate the inclusion of rail lines in any new major logistics developments as an integral planning requirement if it is to come back into contention with wagon/carload based traffic and commodities.
Therefore, this is a nearly optimal solution to the integral bit loading requirement.
The designed controller's poles and zeros are all in the stable region with the exception of one pole at the origin for the integral-action design requirement.
Setting this bandwidth to few hundreds of kHz, and the DCO phase noise to dBc/Hz at 1 MHz offset with 1-MHz corner frequency (between and regions), four TDC bits are sufficient to meet the integral phase noise requirements.
Planning activities were also recognized as being of relevance to elements of the student research experience which were not integral to the requirements of the project.
The biological requirements integral to the survival of a cancer cell are likely very different when it is embedded within a mature tumor microenvironment – composed of stromal fibroblasts, myofibroblasts, and mature matrix – than when it is pushed into the circulation or within immature micrometastatic deposits.
Dan Rooney, the team's owner during most of Nunn's tenure, was integral in devising the requirement that N.F.L. teams interview at least one minority candidate for top coaching and executive positions, which became known as the Rooney Rule.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com