No precise recommendation exists yet about intake of fibre under different conditions of disease.
Parametric tests were used to assess the difference between the mean faecal scores and fibre intake of fibre between the groups.
In the US for example, the estimated daily intake of fibre is app 14 15 g/day or about 50% of what is recommended, and far below the 60 80 g/d of substrate required to maintain a large bowel flora of 1014 microorganisms, known to be typical for a healthy and well-functioning human colon.
Interaction between IL10 C-592A and intake of fibre was found (P-interaction 0.02).
Low intake of fibre, potassium, calcium and vitamin D were also noted on the baseline day.
Fibre density was expressed as absolute intake of fibre (g/d) divided by total daily energy intake (MJ).
The main goals were to substitute unsaturated for saturated fat and to increase the intake of fibre and antioxidants.
Also, interaction between IL10 C-592A and intake of fibre was found (P-value for interaction = 0.02).
Thus, high intake of fibre seems to protect against CRC among individuals with genetically determined low IL10 activity.
High intake of fibre seems to protect against CRC among individuals with IL10 related genetic susceptibility to CRC.
These include intake of fat (risk factor), and intake of fibre, soy protein and vitamins A, C and E (protective factors).
