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In experimental animals, fasting is frequently used in studies where nutritional states need to be synchronized in order to keep biological variation (introduced by varying patterns of food intake) minimal and, thereby, to provide a steady baseline for all measured parameters.
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Our efforts resulted in the identification of compound 4a which significantly reduced food intake with minimal systemic exposure in rodents.
Stimulating muscle protein synthesis is the metabolic basis for maintaining muscle mass, but in cancer patients normal dietary intake has minimal effects on muscle protein synthesis.
The patient has never smoked and alcohol intake was minimal.
CoQ10 is endogenously produced and therefore, dietary intake has minimal influence on the CoQ10 concentration in the body.
Additional adjustment for fiber intake had minimal effect on the summary estimates so it was not included in the final model.
Total caloric intake was minimal on the first day of the replacement phase and thereafter increased slowly to baseline levels (Fig. 1C).
To minimise the chances that any difference was due to medication intake, the minimal follow-up group was sent their study medication by post (Royal Mail) at two-monthly intervals.
Studies using Queensland fruit flies (Fanson et al., 2009), Mexican fruit flies (Carey et al., 2008), Drosophila melanogaster (Min & Tatar, 2006; Lee et al., 2008; Bruce et al., 2013), and field crickets (Maklakov et al., 2008) show that a low-protein/high-carbohydrate diet is associated with long lifespan; however, the overall caloric intake had minimal effects on lifespan (Mair et al., 2005).
Consistent evidence indicates that French consumers of all age groups comply with the PNNS recommendation regarding the frequency of starchy food consumption, but this is achieved with a minimal intake of whole grain cereals.
On the basis of this study, a minimal intake of 320 μg of folate equivalents per day was regarded necessary and this led to the intake recommendation of 400 μg/d.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com