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But a German study published this year suggested that the "critical intake frequency" for developing medication-overuse headaches was only three to four pills a day.
At baseline, 24%% of the patients reported an intake frequency of ≥15 days/month.
Fig. 2 Change in acute medication intake frequency at baseline and follow-up.
The highest reduction of medication intake frequency was found in MOH patients (mean −12.3 days/month).
Intake frequency decreased in the total cohort by about 6.5 days/month and in MOH of about 12.3 days/month.
Finally, the present integrated care program was effective in reducing intake frequency of attack-aborting medication (days/month).
Associations among food preference and intake frequency, activity preference and frequency, and body mass index were examined.
At the end of the study, only 3/193 patients (1.6 %) had an overuse of attack-aborting medications with an intake frequency of ≥15 days/month.
The critical intake frequency for patients with triptan overuse headache, is reported to be 18 single doses of triptans per month [25].
Principal components factor analysis with promax rotation was used to identify 7 patterns that accounted for 45% of the variance of dietary intake frequency.
It is not known whether F/V intake frequency in times per day can be used as a proxy for intake in servings per day.
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