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Both cell lines responded to HU exposure and CDT1 over-expression by inducing phosphorylation of Chk1, an ATR substrate, showing that they both have an intact response to replicative stress.
The largely intact response of these fibroblasts to I+P, and the preservation of many of the transcriptional responses to poly I-C), in the poly I-C of MPV infecthen, contrasts sharpresence the highly specific blofk to induction of IFN- and TNFa-regulated transcripts.
Functional sympatholysis during exercise in patients with type 2 diabetes with intact response to acetylcholine.
This intact response to recall antigens after rituximab has been observed for patients receiving vaccinations [ 24], but has never been documented after natural infection.
Epithelial cells within pre-malignant lesions with markers of senescence maintain an intact response to cellular stress and are less likely to develop subsequent tumors.
The intact response of EBI2-deficient mice to 33D1-Ova was unexpected but suggests that the defective response to SRBC-antigen is not solely a consequence of reduced CD4+ DC numbers.
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By contrast, based on cognitive-experimental evidence, we predicted intact responses in the CP/HCU group.
These pre-naïve B cells showed defective responses to BCR stimulation but intact responses to CD40 ligation, whereas spontaneous apoptosis and cell death were enhanced compared with naïve B cells.
In the first study, neural correlates of prediction error were reduced during learning in older subjects, despite evidence for intact responses to reward outcomes in a task that did not involve learning.
As with studies on Adcy5-/ mice (Herve, 2011; Lee et al., 2002), perhaps the most surprising result of our studies is the intact responses of mice lacking PhLP1 to D1R agonism.
Additionally, immunization of CD4+ T cell-deficient mice [ 48], and mice deficient in CD40L [ 49] (which have defective antibody responses to TD antigens but intact responses to TI antigens) with the PsaA-BLyS fusion may shed more light on the T-dependence or -independence of the response to PsaA-BLyS.
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