Sentence examples for intact recipients from inspiring English sources

Importantly, this tolerance induction protocol also leads to indefinite cardiac allograft survival in immunologically intact recipients 25.

The role of peripheral tissues in sustaining Treg cell populations was elegantly demonstrated by the observation that ablation of a tissue depletes the ability of donor Treg cells to prevent organ-specific autoimmune disease after adoptive transfer into intact recipients, compared with Treg cells from unmodified donors (Seddon and Mason, 1999).

To determine the origin of Tfr cells, naïve Foxp3− TCR-transgenic T cells were transferred into intact recipient mice prior to immunisation.

In contrast to HIV-positive patients, however, CD8 T cells were normally distributed and were functionally intact in ASCT recipients 9 months after.

PCR amplification of the integration site of the PAI prior to its insertion confirmed that it is intact in the recipient strain OG1RF and occupied by the PAI in the transconjugant OG1RFxUW3114 T-12.

PCR amplification confirmed that the identified integration site tRNAlys was intact in the recipient strain 64/3 and occupied by the E. faecalis PAI in the transconjugant 64/3xUW3114 T-1 (Figure 4).

There was no association between ACS and smoking history, hypertension, cholesterol level, intact PTH level, recipient and donor CMV IgG antibody status, donor sex, donor age, dialysis modality before transplantation, immunosuppressive agents, or CMV disease.

OT-II TcR Tg T cells and were adoptively transferred into C57BL/6 or intact MD4 BcR Tg recipients.

Taken together, our results suggest that transferred Tregs induce BM engraftment with unique potency in recipients with intact hematopoietic and immune systems.

Finally, when transplanted into the fat pads of WT or STAT1-/ mice, SSM2 and SSM3 grew only in recipients with intact ovaries or in ovariectomized recipients that received subcutaneous estrogen pellet implants.

By contrast to the observation that FK506 can induce reduced responsiveness to LPS in DCs and macrophages [ 95], Tourneur et al. [ 47] did not evidence marked decrease in either LPS- or Pam3CSK4-induced IL-8 production in intact leukocytes from transplant recipients receiving CsA.