Sentence examples for intact in the mutant from inspiring English sources

On the other hand, polarized dendritic transport of Dscam is not altered in the unc-51 mutant MBs, implying that retrograde dynein/dynactin-mediated transport remains intact in the mutant MB neurons.

sgn3 showed the very same inability of CASP1-GFP to retract from the strips, demonstrating that plasma membrane-to-cell wall attachment remains intact in the mutant.

In contrast to the effects of small molecule allosteric regulators, the substrate-binding pocket is intact in the mutant, yet the enzyme is inactive.

Although we noted that compared to GFP‐gephyrin, less GFP‐G375D‐expressing cells formed CBII‐induced submembranous microclusters (Fig  EV2C), we conclude that this effect is not responsible for the severe cluster deficiency observed in neurons and gephyrin CBII interaction seemed to be intact in the mutant.

Standard kinetics experiments looking at the ATP binding, hydrolysis, product release, and the fluorescence from the ATP sensitive tryptophan (W511) indicate active site kinetics and transmission of force through the Switch 2 helix are fully intact in the mutants.

Contrary to our expectation, the hydrolysis of diubiquitin by the E286A mutant means that the active-site water and the metal are still intact in this mutant.

Furthermore, since the RNA binding region of Tat was still intact in this mutant, this experiment also shows that the RNA binding region is not sufficient to release P-TEFb from the 7SK snRNP.

As discussed above, the UBD located in the C-terminal region is intact in the L157A mutant, which was found ubiquitinated (data not shown).

Consistent with the hemolysis patterns on blood agar, the ausA transposon mutant ΦΝΞ-12202 produced both alpha-hemolysin and SaeP at the wild-type level (Fig. 3B), suggesting that SaeRS signaling is intact in the ausA mutant.

The electron dense layer of heterochromatin immediately interior to the inner nuclear membrane appeared intact in the LMNA mutant heart and was not significantly different in density (n = 15 nuclei).

The Y-shaped links of the ciliary necklace that connect the microtubule doublets to the ciliary membrane in the transition zone; the region of the basal body where the triplet microtubules transition to the doublet microtubules of the axoneme appeared to be intact in the P0 mutant mice.