We hypothesized that loss of Wee1 in the absence of cytotoxics should be able to affect tumor cell proliferation because all metazoan cells, including cancer cells, rely on at least partially functioning checkpoints to insure their survival.
Reversely, fusion of one particular vesicle with the targeted membrane where their content is delivered to insure its function, leads to the dispersion or the active dissociation of many molecular species.
Because of the importance of P-TEFb, regulation must be maintained to insure proper function.
Probably, the effect of the natural selection is to insure the function of the gene, and optimize the expenditure for time, energy, materials, and others.
To insure proper coatings system functions over its desired lifetime, one must have the capability to define, measure and evaluate those system properties that determine these functions in use.
Rait-Kovaleva's text bears an indelible watermark of the Soviet literary establishment, but her domestication of Salinger's language also played a valuable function, insuring that "The Catcher in the Rye" would be printed and widely read, even as it touched on subjects like prostitution and homosexuality that were largely off limits to the country's own writers.
These regulations are enabled to function due to the individual mandate — the requirement to buy insurance or pay a penalty and the limits on open enrollment, without which healthy people might put-off insuring themselves until they got sick.
A new, purely government-owned entity would stand ready to insure mortgages against default when capital markets break down, he said, so that the housing market can continue to function when Wall Street stumbles.
He wants the big regional health-care systems that dominate many metropolitan areas to expand their reach and to assume the function of insuring patients as well.
The use of this new Lyapunov function insures smooth variations of the control variable.
